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Representative publications on the discovery and applications of the SH2 Superbinder technology

Kaneko et al. Superbinder SH2 domains act as antagonists of cell signaling; Sci Signal. 2012 Sep 25;5(243):ra68. doi: 10.1126/scisignal.2003021

Bian et al. Ultra-deep tyrosin phosphoproteomics enabled by a phosphotyrosine superbinder;  Nat Chem Biol. 2016 Nov;12(11):959-966. doi: 10.1038/nchembio.2178. Epub 2016 Sep 19.

Yao et al. One-Step SH2 Superbinder-Based Approach for Sensitive Analysis of Tyrosine Phosphoproteome; J Proteome Res. 2019 Apr 5;18(4):1870-1879. doi: 10.1021/acs.jproteome.9b00045

Chu et al. Photoaffinity-engineered protein scaffold for systematically exploring native phosphotyrosine signaling complexes in tumor samples. Proc Natl Acad Sci USA 2018, 115:E8863-E8872.  DOI: 10.1073/pnas.1805633115

Tong et al. Protein-phosphotyrosine proteome profiling by superbinder-SH2 domain affinity purification mass spectrometry, sSH2-AP-MS; Proteomics 2017 Mar;17(6). doi: 10.1002/pmic.201600360. Epub 2017 Jan 17.